Parkinson’s disease may begin reshaping the body’s chemistry years before the first tremor or stiffness appears. A growing ...
Scientists have found a way to supercharge the immune system’s T cells by blocking a protein called Ant2, essentially rewiring how these cells generate energy. This metabolic reprogramming makes them ...
The study of metabolism within the tumour microenvironment (TME) is a rapidly evolving field that holds significant ...
Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...
Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...
FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...
Potent antitumor activity of the KRASG12D inhibitor MRTX1133 in pancreatic cancer: Augmenting the nanoparticle-paclitaxel chemotherapy response. This is an ASCO Meeting Abstract from the 2025 ASCO ...