Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor ...

Salk Institute researchers find new mode of epigenetic targeting, showing for the first time that genetic sequences can direct new DNA methylation patterns in plants LA JOLLA (November 21, 2025)—All ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

By Pooja Toshniwal Paharia Preclinical studies increasingly place circular RNAs at the intersection of thermogenic programming and organelle stress control, raising the possibility that these stable ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

Although HPVs do express some unspliced mRNAs (Figure 2), most HPV mRNAs are the products of constitutive and alternative splicing. Constitutive splicing is where every intron in the primary RNA ...

Both proteins and DNA can carry marks, called epigenetic markers, that instruct when and which genes are expressed. Although many such markers have been described in proteins, epigenetic marks in DNA ...