Nanowerk

Cytosine in DNA and RNA: Functions, Modifications, and Applications

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...
Morning Overview on MSN

Microscopic droplets reveal DNA’s hidden architecture

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...
GMWatch

Gene editing disrupts multiple gene functions through large-scale epigenetic changes in a way that persists through successive cell generations

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...
AlphaGalileo

A single-site DNA–histone cross-link causes a global breakdown of nucleosome structure and function

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.
Hosted on MSN

DNA folding more important for cell function than previously thought

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.

Scientists capture first detailed look inside droplet-like structures of compacted DNA

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...
Nanowerk

Light-up DNA switches for programmable molecular logic and sensing

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, biosensing, DNA origami integrity reporting, and reusable mRNA detection through ...